![]() More specifically, vitamin D acts as an immune balancing agent, inhibits the exaggeration of immunostimulation. Vitamin D is an essential factor, exhibits immunomodulatory effects by regulating dendritic cells’ maturation, lymphocytes’ functions, and cytokine production. Any difficulties in the cutaneous immune system cause skin diseases (psoriasis, vitiligo, atopic dermatitis, skin carcinoma, and others). ![]() They can synthesize active vitamin D and express vitamin D receptors. The immune cells of the skin exhibit distinct properties. It has a dynamic cellular network with unique immunologic properties to maintain defensive actions, photoprotection, immune response, inflammation, tolerogenic capacity, wound healing, etc. Skin is the largest organ of the body having multifunctional activities. ![]()
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